| Non-smokers | Ever-smokers | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Genotype | Cases/ | OR (95% CI) | Cases/ | OR (95% CI) | ||||||
 | Controls | Crude | P | Adjusted* | P | Controls | Crude | P | Adjusted* | P |
CC + CT | 126/181 | 1.0 (reference) | - | 1.0 (reference) | - | 228/147 | 2.23 (1.64 - 3.03) | <0.01 | 3.03 (2.12 - 4.34) | <0.01 |
TT | 27/28 | 1.39 (0.78 - 2.46) | 0.28 | 1.95 (0.99 - 3.84) | 0.05** | 81/23 | 5.06 (3.02 - 8.47) | <0.01 | 6.16 (3.48 - 10.9) | <0.01 |
Crude Pinteraction = 0.21 and adjusted Pinteraction = 0.93 | ||||||||||
 | Appropriate drinkers | Excessive drinkers | ||||||||
Genotype | Cases/ | OR (95% CI) | Cases/ | OR (95% CI) | ||||||
 | Controls | Crude | P | Adjusted* | P | Controls | Crude | P | Adjusted* | P |
CC + CT | 128/177 | 1.0 (reference) | - | 1.0 (reference) | - | 226/151 | 2.07 (1.52 - 2.81) | <0.01 | 1.97 (1.38 - 2.82) | <0.01 |
TT | 50/27 | 2.56 (1.52 - 4.31) | <0.01 | 2.46 (1.37 - 4.43) | <0.01 | 58/24 | 3.34 (1.97 - 5.66) | <0.01 | 3.09 (1.64 - 5.81) | <0.01 |
Crude Pinteraction = 0.22 and adjusted Pinteraction = 0.30 |