Table 3 Chemotherapy characteristics and on-treatment toxicities
Variables | Number |
|---|---|
Total number of cycles | 98 |
Fluorouracil | 97^ |
Cisplatin | 94* |
Patients receiving | |
2 cycles | 5 (17.2%) |
3 cycles | 12 (41.4%) |
4 cycles | 12 (41.4%) |
Cisplatin modification (total # of cycles = 94) | |
Full dose-intensity | 70 (74.5%) |
Delay/modification | 24 |
Cisplatin and/or Fluorouracil modification (total # of cycles over the first 2 cycles = 58) | |
Full dose-intensity | 49 (70.7%) |
Delay/modification | 9 |
Reasons | |
Haematological toxicities | 2 |
Neutropenia (G3) | 1 |
Leucopoenia (G1) | 1 |
Non Haematological toxicities | 5 |
Diarrhoea (G2) | 1 |
Nausea (G2 and G3) | 2 |
Nausea and Diarrhoea (G2) | 1 |
Mucositis (G2) | 1 |
Haematological and non-haematological toxicities | 1 |
Diarrhoea (G2) and Leucopoenia (G2) | 1 |
Other toxicities | 1 |
Hypoacusia (G2) | 1 |