Figure 4From: Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma GPR39 promotes cell mobility and invasion by inducing partial EMT and remodeling cytoskeleton. (A) Representatives of cell morphology of GPR39-expressing cells and Vec-30 cells (original magnification × 200). (B) Expressions of epithelial markers E-cadherin and mesenchymal markers fibronectin, N-cadherin, and vimentin, were compared by RT-PCR or Western blotting analysis between GPR39-expressing cells and Vec-30 cells. GAPDH was used as loading control. (C) Representative images of F-actin staining. Formation of lamellipodia (indicated by arrows) was stimulated by GPR39 compared to control cells (magnification × 400).Back to article page