Table 2 Patients and tumor characteristics in dependence of the intratumoral OCT1 mRNA expression

N

27

26

Median follow-up in days (range)

434 (22-1538)

425 (109-1645)

n.s. (0.20)

Male/female (n)

23/4

23/3

n.s. (1.00)

Median age in years (range)

69 (35-86)

67 (47-93)

n.s. (0.35)

1-3 nodules/multiple nodules (specimen)

18/9

18/8

n.s. (1.00)

Tumor diameter < 3 cm/> 3 cm

5/22

14/12

0.010

Median tumor diameter in cm (range)

6.0 (1.5-30)

2.8 (0.1-20)

0.035

T classification: T1/T2/T3 (specimen)

8/7/12

10/13/3

0.025

Grading: G1/G2/G3/Gx

1/17/9/0

10/14/1/1

0.001

AFP > 100/< 100 *

9/16

2/24

0.019

Angioinvasion yes/no ^#

7/16

4/22

n.s. (0.31)

Child A/B/C/no cirrhosis

10/1/1/15

9/3/6/8

n.s. (0.08)

Underlying disease (HCV/HBV/alcoholic/others/unknown)

4/2/1/10/10

6/7/3/5/5

n.s. (0.11)

SLC22A3 mRNA expression

ratio HCC/TST (range)

0.21

(0.001-3.07)

0.86

(0.33-3.12)

0.008

Pretreatment with chemoembolization (yes/no)

2/25

18/8

< 0.001

Liver transplantation/resection

4/23

16/10

0.001