Table 2 Characteristics of 11 patients with not evaluable or uncertain brain response
Case No | Study drug started | Study drug ended | Reason for ending drugs | Best systemic response | Brain PD by symptoms and MRI | Reason for not evaluable brain response during study period | Inclusion* |
|---|---|---|---|---|---|---|---|
1 | Consent withdrawal | ● | |||||
2 | 2007.3.22 | 2007.3.29 | Unknown | Unknown | Unknown | No follow-up MRI | ● |
3 | 2008.2.19 | 2008.3.11 | Unknown | Unknown | Unknown | No follow-up MRI | ● |
4 | 2008.2.15 | 2008.4.1 | Systemic PD | PD | Unknown | No follow-up MRI | ● |
5 | 2007.3.22 | 2007.4.17 | Systemic PD | PD | Unknown | No follow-up MRI | ● |
6 | 2007.8.07 | 2007.9.17 | Systemic PD | PD | 2008.2.18 | MRI long after ending study drug | ●, ◊ |
7 | 2007.4.02 | 2008.5.21 | Brain PD | PR | 2008.6.3 | No MRI until brain symptoms | ●, ◊ |
8 | 2007.3.30 | 2007.6.28 | Systemic PD | PR | 2007.11.12 | Metastatectomy prior to study started | ◊ |
9 | 2007.11.30 | 2008.2.5 | Systemic PD | SD < 6mo | 2008.7.30 | Metastatectomy prior to study started | ◊ |
10 | 2008.4.8 | 2008.11.11 | Systemic PD | SD ≥ 6mo | 2008.11.7 | Metastatectomy prior to study started | ◊ |
11 | 2007.9.5 | 2007.12.31 | Systemic PD | SD < 6mo | 2008.2.3 | Gamma knife surgery prior to study started | ◊ |