Figure 2

Brevican overexpression promoted cell adhesion and migration. (A) Brevican expression levels of stably transduced pMX-brevican cells were higher than those of control cells (B) Brevican expression enhanced fibronectin-dependent cell adhesion. PL, poly-L-lysine; FN, fibronectin. (C) Stably transduced U251 and U87 cells demonstrated migration through transwell inserts. Cells were stained with HE (200×), and the experiments were repeated at least three times; a: U251-MO; b: U251-BR; c: U87-MO; d: U87-BR; MO, the transduced cells with pMX-mock; BR, the transduced cells with pMX-brevican. * P < 0.05; ** P < 0.01.