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Table 2 Expression of BCA2 and hHR23a in breast cancer cases

From: Effects of partner proteins on BCA2 RING ligase activity

 

Cytoplasmic BCA2

Nuclear BCA2

Cytoplasmic hHR23a

Nuclear hHR23a

Variable

Low (%)

High (%)

P-value

Low (%)

High (%)

P-value

Low (%)

High (%)

P-value

Low (%)

High (%)

P-value

ER

                    

Positive

27

(34.2)

52

(65.8)

0.8053

29

(36.7)

50

(63.3)

0.4772

27

(34.2)

52

(65.8)

*0.0181

39

(50.0)

39

(50.0)

0.4947

Negative

7

(29.2)

17

(70.8)

 

11

(45.8)

13

(54.2)

 

2

(8.3)

22

(91.7)

 

10

(41.7)

14

(58.3)

 

PR

                    

Positive

17

(31.3)

39

(68.7)

0.6743

17

(30.4)

39

(69.6)

0.0686

19

(33.9)

37

(66.1)

0.1897

26

(47.3)

29

(52.7)

1.000

Negative

17

(36.1)

30

(63.9)

 

23

(48.9)

24

(51.1)

 

10

(21.3)

37

(78.7)

 

23

(48.9)

24

(51.1)

 

HER2

                    

Positive

6

(35.3)

11

(64.7)

1.000

8

(47.1)

9

(52.9)

0.5878

5

(29.4)

12

(70.6)

1.000

10

(58.8)

7

(41.2)

0.4292

Negative

28

(32.9)

57

(67.1)

 

32

(37.6)

53

(62.4)

 

23

(27.1)

62

(72.9)

 

39

(46.4)

45

(53.6)

 

Grade

                    

1

2

(22.2)

7

(77.8)

0.5501

4

(44.4)

5

(55.6)

* 0.0297

3

(33.3)

6

(66.7)

0.2730

5

(55.6)

4

(44.4)

0.4142

2

18

(38.3)

29

(61.7)

 

12

(25.5)

35

(74.5)

 

14

(29.8)

33

(70.2)

 

19

(41.3)

27

(58.7)

 

3

14

(30.4)

32

(69.6)

 

24

(52.5)

22

(47.8)

 

12

(26.1)

34

(73.9)

 

25

(54.3)

21

(45.7)

 

Nodal

                    

Positive

11

(32.4)

23

(67.6)

1.000

10

(29.4)

24

(70.6)

0.1952

14

(41.2)

20

(58.8)

0.0585

17

(51.5)

16

(48.5)

0.6649

Negative

20

(33.3)

40

(66.7)

 

26

(43.3)

34

(56.7)

 

13

(21.7)

47

(78.3)

 

27

(45.0)

33

(55.0)

 
  1. * Indicates a correlation which is statistically significant by Fisher's exact t-test or χ 2 test
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