Figure 5From: Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer Copy number analysis of CTCs versus matched archival tumor in two patients. Array CGH analysis of (A) 20 CTCs from patient #17 and a corresponding archival primary tumor from local extension to the bladder obtained 1 year and 3 months prior to CTC analysis; and (B) 18 CTCs from patient #20 and a matched primary tumor obtained 5 years and 1 month prior to CTC analysis. Arrows indicate high-level gains on X chromosome region containing AR in CTCs but not observed in archival primary tumors. Chromosome regions in red boxes show genomic aberrations common to both paired samples (Also see Additional file 3: Figure S3).Back to article page