Figure 1From: p53-independent early and late apoptosis is mediated by ceramide after exposure of tumor cells to photon or carbon ion irradiation Time course of ceramide production in SCC61, SF767, SQ20B, and U87MG cell lines after a 10Gy irradiation with photons or 33.4 or 184 keV/μm carbon ions. Early ceramide production (A) was quantified by fluorencence microscopy and late ceramide (B) by HPLC. Values represent the mean ± SD of two or three independent experiments performed in triplicate. *p < 0.05, **p < 0.01, and ***p < 0.001 compared to control.Back to article page