Figure 5From: Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc −/+ ice Western blot analysis of pRb, cyclin D1, Cdk4, and Rb. A: Analysis of cyclin D1 and pRb in total cell lysates from HT-29 cell line treated with 0.1, 0.5, 1, 10, 100 μM of silibinin. B and C: Analysis of cyclin D1, pRb, Cdk4, and Rb of the mucosal cells lining the intestine after silibinin administration for 5 days. The blots were re-probed using β-actin as a loading control.Back to article page