A) Published studies of association with Melanoma | |||||||
Study | Gene | SNP | Allele | OR | p-value | MM association | |
MacGregor et al. 2011 | PARP1 | rs3219090 | A | 0.82 | 9.5 × 10-7 | Protective | |
Barrett et al. 2011 | ATM | rs1801516 | A | 0.79 | 4.80 × 10-7 | Protective | |
CASP8 | rs13016963 | A | 1.18 | 5.68 × 10-7 | Risk | ||
MX2 | rs45430 | G | 0.85 | 5.60 × 10-7 | Protective | ||
CCND1 | rs1485993 | A | 1.19 | 4.15 × 10-7 | Risk | ||
Duffy et al. 2010 | IRF4 | rs12203592 | C | 1.15 | 4 × 10-3 | Protective | |
B) Previous studies of association with Vitamin D levels | |||||||
Published Data | |||||||
[VitD] < 75 nmol/L levels | [VitD] < 50 nmol/L levels | ||||||
Study | Gene | SNP | Allele | OR (CI 95%) | p-value | OR (CI 95%) | p-value |
Wang et al. 2011 | CYP2R1 | rs10741657 | A | 1.21 (1.45-1.29) | 9.4 × 10-11 | 1.06 (1.00-1.13) | 0.06 |
NADSYN1 | rs7944926 | A | 1.21 (1.14-1.29) | 4.1 × 10-10 | 1.21 (1.14-1.29) | 4.7 × 10-9 | |
NADSYN1 | rs12785878 | G | - | - | - | - |