Figure 4

Effect of FLC diets on the survival of mice through 16 weeks post-XRT. Kaplan-Meier curves for overall survival. Mice were pre-fed 0% FLC for 72 hours prior to single fraction thoracic X-ray radiation therapy (13.5 Gy). Following XRT exposure, mouse cohorts (n=15) were fed 10% FLC or 20% FLC diets initiated Panel A: 24, Panel B: 48 or Panel C: 72 hours post-XRT and survival was observed up to 16 weeks post-XRT. Control-fed mouse cohorts remained on 0% FLC diet throughout the course of the study. No mice were lost in the non-irradiated cohorts (100% survival-not shown). Log-rank p-values (shown in figure) were calculated by log-rank test between irradiated mouse cohorts. Overall survival at 16 weeks post-XRT is depicted in the bar graph.