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Table 1 Clinical and molecular characteristics of 98 patients with rectal carcinoma

From: Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery

Clinical and molecular characteristics

No patients n=98 (%)

Sex

 

Male

50 (51)

Female

48 (49)

Age. y median

68 (35–88)

Distance to anal verge. cm

 

≥10

25 (25.5)

5≤ <10

26 (26.5)

<5

40 (41.8)

Not avaibale

7 (7.2)

Type of resection

 

Low anterior

8 (8.1)

Abdominoperineal

90 (91.9)

CRM

 

Negative

88 (89.8)

Positive

3 (3.1)

Not avaiballe

7 (7.1)

Differentiation

 

Well

15 (15.1)

Moderate

51 (52.1)

Poor

10 (10.3)

Not avaibale

22 (22.5)

TNM stage

 

I

6 (6.1)

II

86 (87.8)

II

6 (6.1)

KRAS mutation

 

Yes

23(23.5%)

No

75 (76.5)

BRAF mutation

 

Yes

2 (2%)

No

96 (98%)

PIK3CA mutation

 

Yes

4 (4%)

No

94 (96%)

Local recurrence

 

Negative

90 (91.8)

Positive

8 (8.2)

Distant metastasis

 

Negative

81 (82.6)

Positive

17 (17.4)