Table 1 Baseline characteristics and Annexin A1 expression
Characteristics | Total | Annexin A1 expression | P value* | |
|---|---|---|---|---|
patients | Low | High | ||
N=256 | N=96 | N=136 | ||
n (%) | n (%) | n (%) | ||
Gender | ||||
 Male | 179 (69.9) | 72 (77.2) | 88 (61.0) | 0.095 |
 Female | 77 (30.1) | 24 (22.8) | 48 (39.0) |  |
Age (years) | ||||
 <60 | 168 (65.6) | 67 (71.1) | 90 (64.4) | 0.562 |
 ≥60 | 88 (34.4) | 29 (29.9) | 46 (35.6) |  |
Site | ||||
 Tongue | 113 (44.1) | 42 (42.1) | 56 (42.4) | 0.281 |
 Buccal | 45 (17.6) | 15 (17.5) | 28 (20.3) |  |
 Gingiva | 40 (15.6) | 11 (12.3) | 27 (21.1) |  |
 Floor of mouth | 30 (11.7) | 16 (16.7) | 13 (8.5) |  |
 Palate | 18 (7.0) | 7 (6.1) | 7 (5.9) |  |
 Retromolar trigone | 10 (3.9) | 5 (6.1) | 5 (2.5) |  |
Clinical T descriptor | ||||
 T1/T2 | 66 (25.8) | 23 (24.6) | 38 (28.0) | 0.497 |
 T3/T4 | 190 (74.2) | 73 (75.4) | 98 (72.0) |  |
Clinical N descriptor | ||||
 N0 | 110 (43.0) | 40 (39.5) | 59 (45.8) | 0.480 |
 N1 | 94 (36.7) | 33 (39.5) | 53 (34.7) |  |
 N2 | 52 (20.3) | 23 (21.0) | 24 (19.5) |  |
Clinical stage | ||||
 III | 177 (69.1) | 60 (65.8) | 100 (72.0) | 0.074 |
 IVA | 79 (30.9) | 36 (34.2) | 36 (28.0) |  |
Pathologic differentiation | ||||
 Well | 80 (31.2) | 18 (22.8) | 47 (33.1) | 0.015 |
 Moderately | 165 (64.5) | 71 (71.1) | 85 (63.6) |  |
 Poorly | 11 (4.3) | 7 (6.1) | 4 (3.4) |  |
Smoking status** | ||||
 Current/former | 126 (49.2) | 52 (56.1) | 58 (39.0) | 0.084 |
 Never | 130 (50.8) | 44 (43.9) | 78 (61.0) |  |
Alcohol use*** | ||||
 Positive | 98 (40.6) | 44 (48.2) | 44 (28.0) | 0.037 |
 Negative | 158 (59.4) | 52 (51.8) | 92 (72.0) |  |