Figure 6
From: Axin gene methylation status correlates with radiosensitivity of lung cancer cells
The effect of 5-Aza and TSA treatment on lung cancer cell lines with hypermethylated Axin gene or unmethylated Axin gene. The Axin mRNA expression is significantly up-regulated in H157 cells after 5-Aza treatment or TSA treatment. Further increases in Axin transcripts are detected after combined use of 5-Aza and TSA in the H157 cells (A and B) but not in LTE cells (C and D). ** P<0.01, in comparison with control group (cells with no treatment).