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Table 1 Percent (%) MM tumor distribution a

From: Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts

 

Saline

APMS-MB

DOX low (0.05 mg/kg)

APMS-MB-DOX (0.05 mg/kg)

DOX high (0.2 mg/kg)

Injection site

4.17

2.38

4.17

5.56

0.00

Pleura

0.00

0.00

3.33

0.00

0.00

Diaphragm

4.76

0.00

0.00

0.00

0.00

Esophagus

0.00

0.00

0.00

2.78

2.38

Liver

10.91

5.16

2.78

4.86

11.62

Kidney

4.44

3.97

6.11

9.33

8.49

Gut

8.33

19.60

12.36

15.56

4.17

Stomach

11.67

13.10

18.06

15.63

7.45

Spleen

4.52

14.21

11.25

20.38

7.04

Intestine

26.43

28.89

25.00

14.64

36.47

Bladder

0.00

0.00

0.00

0.00

2.78

Ovaries/Testes/Vas deferens

24.76

12.70

16.94

11.27

19.60

  1. aAs measured by the average percent (%), per treatment group, of the number tumors recovered found attached to or adjacent to respective organs and areas.