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Figure 5 | BMC Cancer

Figure 5

From: 3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing

Figure 5

Analyses of extracellular matrix related genes. [A] mRNA expression of ECM relevant genes in 2D and 3D cultures. Real Time-PCR data are calculated as expression ratio 3D/2D. A representative experiment is shown [B] Collagen I and fibronectin I staining of a central section from 7 day spheroids (right). One representative picture is shown. Secondary antibody alone staining is used as negative control (CTR, left). [C] ECM-relevant time course of selected miRNA expression in 2D and 3D cultures. Real Time-PCR data are calculated as expression ratio 3D/2D. A representative experiment out of three is shown.

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BMC Cancer

ISSN: 1471-2407

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