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Table 2 Overall survival in NEC cohort and invasive mammary carcinoma cohort according to clinical stage (2003–2009)

From: Invasive neuroendocrine carcinoma of the breast: a population-based study from the surveillance, epidemiology and end results (SEER) database

Cohort

n

Median survival in months (IQR)

5-year OS rate (95% CI)

P

All

   

<0.0001

NEC

135

26 (12–48)

53.6 (42.2-63.7)

 

IMC

374,598

34 (16–56)

79.8 (79.6-79.9)

 

Stage I

   

0.002

NEC

32

33 (17–51)

74.4 (43.4-90.0)

 

IMC

170,778

36 (18–58)

89.6 (89.2-89.6)

 

Stage II

   

<0.0001

NEC

49

30 (19–52)

73.9 (56.3-85.3)

 

IMC

123,430

36 (17–58)

82.4 (82.1-82.7)

 

Stage III

   

0.014

NEC

16

19 (13–41)

58.2 (21.0-82.8)

 

IMC

41,422

29 (14–48)

72.4 (71.8-73.1)

 

Stage IV

   

NS

NEC

32

12 (4–25)

20.7 (5.70-42.1)

 

IMC

17,830

15 (5–30)

27.9 (26.9-29.0)

 
  1. Data from the Surveillance, Epidemiology and End Results Program, 2003 to 2009. NEC, neuroendocrine carcinoma; IMC, invasive mammary carcinoma; IQR, interquartile range; OS, overall survival; n, number of cases; HR, hazard ratio; CI, confidence interval; NS, not significant.