Table 5 Multivariate analysis of independent prognostic factors for DSS and OS in patients with invasive carcinoma of the breast (pooled NEC and IMC-NOS)
Group | DSS | OS | ||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Age, years (>60 vs ≤60) | 1.14 (1.13-1.16) | <0.0001 | 2.62 (2.60-2.65) | <0.0001 |
Tumor size, mm (>20 vs ≤20) | 1.65 (1.64-1.66) | <0.0001 | 1.34 (1.33-1.35) | <0.0001 |
LN (positive vs negative) | 1.98 (1.97-2.00) | <0.0001 | 1.64 (1.63-1.65) | <0.0001 |
Grade (III vs I, II) | 1.26 (1.25-1.27) | <0.0001 | 1.12 (1.11-1.13) | <0.0001 |
ER status (positive vs negative) | 0.82 (0.81-0.83) | <0.0001 | 0.90 (0.89-0.91) | <0.0001 |
PR status (positive vs negative) | 0.88 (0.87-0.89) | <0.0001 | 0.93 (0.92-0.94) | <0.0001 |
Neuroendocrine (positive vs negative) | 1.80 (1.36-2.37) | <0.0001 | 1.84 (1.50-2.26) | <0.0001 |
Radiation (yes vs no) | 0.90 (0.89-0.91) | <0.0001 | 0.75 (0.74-0.76) | <0.0001 |
Surgery (yes vs no) | 0.44 (0.43-0.45) | <0.0001 | 0.45 (0.46-0.47) | <0.0001 |