Figure 2

Knockdown of KIAA1199 inhibits cell migration and proliferation in vitro . A) The wound-healing assay shows significantly lower cell motility in the KIAA1199 knockdown cells (MDA-MB-231-ShA and MDA-MB-231-ShB) compared to the negative controls. B) Trans-well assay shows a decrease in the cell migration rate (migrated/total) for the KIAA1199 knockdown cells (the experiment was performed in three biological replicates). C) The MTT assay demonstrates that both MDA-MB-231 and Hs578T knockdown cells have significantly lower proliferation levels at 72 and 96 h of culture (the experiment was performed in three biological replicates).