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Figure 3 | BMC Cancer

Figure 3

From: The pemetrexed-containing treatments in the non-small cell lung cancer, is -/low thymidylate synthase expression better than +/high thymidylate synthase expression: a meta-analysis

Figure 3

Comparison of objective response rate between the TS -/low arm and TS +/high arm of NSCLC patients receiving pemetrexed-containing chemotherapy (n = 526). Pooled data from these 8 studies showed an overall objective response rate of 19.3% and 30.0% for TS +/high expression (n = 269) and TS -/low expression (n = 257), respectively, which was significantly in favor of TS -/low expression (OR = 0.45; 95% CI, 0.29–0.70; p = 0.0004).

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