Indoleamine 2,3-dioxygenase (IDO) is frequently expressed in stromal cells of Hodgkin lymphoma and is associated with adverse clinical features: a retrospective cohort study

Table 2 Correlation between IDO expression, cellular infiltration and EBV positivity in HIV negative classical Hodgkin lymphoma

		CD163	CD68	Mono	CD8	CD4	FOXP3 /CD4	Subtype	EBV
IDO	r	0.439	0.493	0.225	0.368	-0.200	0.210	0.433	0.158
IDO	P-value	<0.001	<0.001	0.026	<0.001	0.060	0.048	<0.001	0.150
CD163	r		0.668	0.179	0.194	0.102	-0.116	0.234	0.092
CD163	P-value		<0.001	0.107	0.084	0.360	0.301	0.028	0.434
CD68	r			0.229	0.240	0.206	-0.084	0.197	0.118
CD68	P-value			0.044	0.034	0.069	0.461	0.072	0.328
Monocyte	r				0.109	-0.183	0.211	0.190	0.170
Monocyte	P-value				0.329	0.094	0.053	0.062	0.129
CD8	r					0.123	0.009	0.368	-0.103
CD8	P-value					0.264	0.936	<0.001	0.397
CD4	r						-0.788	-0.261	-0.197
CD4	P-value						<0.001	0.014	0.092
FOXP3 /CD4	r							0.090	0.164
FOXP3 /CD4	P-value							0.402	0.164
Subtype	r								0.274
	P-value								0.011

r, correlation coefficient; IDO, indoleamine 2,3-dioxygenase; EBV, Epstein-Barr virus; HIV, human immunodeficiency virus.

ISSN: 1471-2407