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Table 5 Characteristics of Hodgkin lymphoma patients according to IDO expression

From: Indoleamine 2,3-dioxygenase (IDO) is frequently expressed in stromal cells of Hodgkin lymphoma and is associated with adverse clinical features: a retrospective cohort study

Variable

IDO high

IDO low

Sex

Male

Female

Age group

Older

Young

Histologic type

MC, LD, LR

NLP, NS

Ann Arbor stages

Advanced stage

Limited stage

IPS

High

Low

B symptom

Present

Absent

EBV or HIV infection

positive

Not accompanied

FOXP3/CD4*

High

Low

  1. *FoxP3/CD4 significantly correlated with IDO in cases with limited stages.
  2. IDO, indoleamine 2,3-dioxygenase; MC, mixed cellularity; LD, lymphocyte-depleted; LR, lymphocyte-rich; NLP, nodular lymphocyte predominant; NS, nodular sclerosis; IPS, international prognostic score.