From: Alcohol induces cell proliferation via hypermethylation of ADHFE1 in colorectal cancer cells
Characteristics | No. of cases | Methylation status of ADHFE1(PMR, %) | |
---|---|---|---|
Median (range) | p-Value | ||
Normal | 73 | 3.25 (±0.50) | < 0.001† |
Colorectal cancer | 73 | 74.89 (±8.06) | |
Age (years) | 0.957 | ||
≤ 65 | 35 | 75.35 (±13.73) | |
> 65 | 38 | 74.46 (±9.13) | |
Gender | 0.114 | ||
Female | 27 | 91.55 (±16.46) | |
Male | 46 | 65.10 (±8.21) | |
Location | 0.627 | ||
Colon | 46 | 77.91 (±10.45) | |
Rectum | 27 | 69.73 (±12.77) | |
TNM Stage | 0.252 | ||
I,II | 32 | 85.40 (±14.10) | |
III,IV | 41 | 66.68 (±9.18) | |
Size (mm) | 0.276 | ||
≤ 25 | 44 | 67.71 (±7.81) | |
> 25 | 29 | 85.78 (±16.48) | |
Alcohol consumption | 0.012† | ||
Non-drinking | 36 | 95.27 (±13.15) | |
Drinking | 37 | 55.06 (±8.41) |