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Table 1 SW480 intracellular tocopherol concentrations (pmoles/well) after 24 hour treatments with 5 or 10 μM tocopherols as determined by HPLC analysis. The result is an average of three trials and the Standard Error of the Mean (SEM) is reported. γ-Tocopherol incorporates into the SW 480 cells at levels up to 20-fold that of α-tocopherol at the same treatment concentration.

From: Gamma (γ) tocopherol upregulates peroxisome proliferator activated receptor (PPAR) gamma (γ) expression in SW 480 human colon cancer cell lines

Treatment Cell Line

Mean Tocopherol Concentration (pmole/well) N

Standard Error of Mean

5 μM α-tocopherol

10.20

4.11

SW-480 cells

3

 

5 μM γ-tocopherol

197.5

49.52

SW-480 cells

3

 

10 μM α-tocopherol

17.42

5.81

SW-480 cells

3

 

10 μM γ-tocopherol

360.54

69.97

SW-480 cells

3

 

5 μM α-tocopherol

4.10

N/A

LOVO cells

1

 

5 μM γ-tocopherol

152.50

N/A

LOVO cells

1