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Table 8 Bladder

From: Effects of non-steroidal anti-inflammatory drugs on cancer sites other than the colon and rectum: a meta-analysis

Author

Cases N

Controlsa/Cohortb

Source Population

Exposure definition

Exposure assessment

Drug

RR

95% CI

Castelao et al. [25]

1,514

1,514a

Population based

>2 days/week for >1 month

Personal Interview

Aspirin (12%) †

0.85

0.66–1.09

      

NSAIDs (39%)

0.81

0.68–0.96

Langman et al. [36]

1,041

3,122a

Population based

>7 prescriptions during months 13–36 before index date

Automated Database

NSAIDs (7%)

1.14

0.85–1.53

Rosenberg[56]

1,110

4,906a

Hospital based

>3 days/week for >3 months 1.5 years of lag time

Personal Interview

NSAIDs (6%)

0.8

0.4–1.6

Paganini-Hill et al. [40]

93

13,987b

Cohort

Daily use of aspirin for an undefined time

Mailed questionnaire

Aspirin (16%)

1.10§

0.65–1.85

Schreinemachers et al. [43]

35

12,668b

Cohort

Ever use of aspirin in the 30 days prior to start date

Personal Interview

Aspirin (59%)

1.06

0.54–2.09

  1. Prevalence of exposure among controls/cohort; †Exclusive users of aspirin.