Table 2 IC50values obtained after 24 h exposure to TPL followed by 72 h incubation in drug free medium. (mean ± s.e.m. of 4–6 independent experiments).
From: Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin
Cell lines | IC25 (μM) | IC50 (μM) | R.I.a |
|---|---|---|---|
HCT116 | 280.00 ± 39.21 | 560.00 ± 77.78 | 1.0 |
HT29 | 320.40 ± 50.03 | 665.63 ± 102.91 | 1.19 |
HCT116 E6 | 400.06 ± 60.00 | 837.3 ± 103.99 | 1.49 |
HCT116 p21-/- | 700.00 ± 99.14 | 1114.55 ± 182.2 | 1.99 |