Table 4 Comparison of difference in gene expression between combination treatment and mono-treatment in PC3 cells
Gene | Taxotere+Furtulon | ||
|---|---|---|---|
| Â | 6 h | 36 h | 72 h |
Decrease in combination treatment, No change or increase in mono-treatment. | Â | Â | Â |
NM_001261.1 cyclin-dependent kinase 9 (CDC2-related kinase) (CDK9) | -1.3 | -1.2 | -2.3 |
NM_016507.1 CDC2-related protein kinase 7 (CrkRS) | NC | -1.6 | -2.3 |
AF080157.1 IkB kinase-a (IKK-alpha) | NC | -2.0 | -1.6 |
U62296.1 transcription factor NF-YC | -1.1 | -1.7 | -2.3 |
BC005003.1 nuclear transcription factor Y, gamma | -1.1 | -2.0 | -2.1 |
BC001771.1 transcription factor IIF | NC | -1.6 | -2.3 |
AI434345 activating transcription factor 1 | NC | -2.5 | -2.6 |
BC001173.1 eukaryotic translation initiation factor 3 | NC | -1.3 | -2.0 |
U78525.1 eukaryotic translation initiation factor (eIF3) | NC | -1.4 | -2.0 |
NM_001814.1 cathepsin C (CTSC) | NC | -1.3 | -2.0 |
NM_003377.1 vascular endothelial growth factor B (VEGFB) | -2.1 | NC | NC |
AF035620.1 BRCA1-associated protein 2 (BRAP2) | -2.3 | NC | NC |
AF035620.1 BRCA1-associated protein 2 (BRAP2) | -2.3 | -2.0 | -1.4 |
NM_005346.2 heat shock 70 kD protein 1B (HSPA1B) | -1.1 | -2.1 | -1.1 |
BC000478.1 heat shock 70 kD protein 9B | NC | -1.7 | -2.3 |
NM_014278.1 heat shock protein (hsp110 family) (APG-1) | -1.2 | -1.3 | -2.0 |
BC002526.1 Similar to heat shock protein, 110 kDa | -1.1 | -1.4 | -2.1 |
Increase in combination treatment, No change or decrease in mono-treatment. | Â | Â | Â |
NM_000077.1 cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4) | NC | 1.7 | 2.1 |
NM_001262.1 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | NC | 2.1 | 2.0 |
J03202.1 laminin B2 chain mRNA | NC | 1.3 | 2.0 |
BG164365 microtubule-associated protein 1B | NC | 2.3 | 2.0 |
NM_000594.1 tumor necrosis factor, member 2 | NC | 2.5 | 1.6 |
NM_001065.1 tumor necrosis factor, member 1A | NC | 2.0 | 1.9 |
BC000125.1 Similar to transforming growth factor, beta 1 | -1.2 | 1.9 | 2.1 |
NM_005649.1 transcription factor 17 (TCF17) | NC | 1.1 | 2.3 |
NM_005923.2 mitogen-activated protein kinase kinase kinase 5 (MAP3K5) | NC | 1.6 | 2.1 |
NM_005204.1 mitogen-activated protein kinase kinase kinase 8 (MAP3K8) | NC | 2.3 | 4.3 |
NM_000785.1 cytochrome P450, subfamily XXVIIB | NC | 2.1 | 1.5 |
NM_002960.1 S100 calcium-binding protein A3 (S100A3) | NC | 2.5 | 2.5 |
NM_002962.1 S100 calcium-binding protein A5 | NC | 8.6 | 10.6 |