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Table 3 Comparison of LD groups for the Utah breast cancer cases and controls with Applied Biosystems (ABI) data*

From: Characterization of the linkage disequilibrium structure and identification of tagging-SNPs in five DNA repair genes

Gene

Group

Utah breast cancer case/control SNPs

Utah potential tSNPs

Utah % variance captured/group

ABI SNPs

ABI potential tSNPs

ABI % variance captured/group

ATM

1

A1-A14

A1-A3, A5, A6, A8-A10, A12-A14

98.8%

A1-A14

A1-A3, A5, A8, A13, A14

98.2%

MRE11

1

M1, M2, M3, M5, M6

M1, M2, M3, M5, M6

100%

M1, M2, M3, M5, M6

M1, M2, M3, M5, M6

100%

 

2

M7, M9, M10

M10

84.3%

M7, M9, M10

M7, M9, M10

100%

 

3

M11

M11

100%

M11

M11

100%

 

4

M4, M8

M4, M8

82.2%

M4, M8

M4, M8

83.9%

XRCC4

1

X1-X8, X10-X13

X2-X3, X5-X8, X10-X11

95.3%

X1-X8, X10-X13

X2, X3, X10, X11, X13

96.0%

 

2

X14, X16-X18

X14

91.6%

X14, X16-X18

X14, X17, X18

93.5%

 

3

X19-X21

X19-X21

100%

X19-X21

X19-X21

100%

 

4

X9, X15

X9, X15

97.4%

X9, X15

X9, X15

96.8%

  1. *We used Applied Biosystems' validated SNP genotype data for 45 Caucasian subjects.