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Table 3 Univariate analysis of potential prognostic factors for survival of 99 advanced serous epithelial ovarian carcinoma patients

From: WT1 gene expression as a prognostic marker in advanced serous epithelial ovarian carcinoma: an immunohistochemical study

Characteristic

Hazard ratio

95%CI

p-value

1. FIGO Staging

   

   III

1

-

0.6188

   IV

1.21

0.58–2.56

 

2. Histologic grade

   

   1

1

-

0.6569

   2

1.31

0.74–2.30

 

   3

1.13

0.86–2.26

 

3. Residual tumor (cm)

   

   None

1

-

0.3046

   >0–≤1

2.24

0.79–6.37

 

   >1–≤2

0.99

0.21–4.62

 

   >2

1.75

0.87–3.66

 

4. Chemotherapy response

   

   Complete

1

-

0.0001

   Partial

0.99

0.39–2.53

 

   Stable

3.47

1.52–7.91

 

   Progressive

3.80

2.12–6.82

 

5. WT1 staining

   

   No

1

-

0.0001

   Yes

2.79

1.70–4.57

 

6. Percent staining

   

   0

1

-

0.0008

   1–25

4.05

1.89–8.70

 

   26–50

2.50

1.30–4.82

 

   51–75

1.97

0.86–4.54

 

   ≥76

3.58

1.61–7.96

 

7. Intensity

   

   0

1

-

0.0002

   1+

2.56

1.47–4.48

 

   2+ or 3+

3.23

1.70–6.14