From: GSTT2 promoter polymorphisms and colorectal cancer risk
Locus | HWE | MAF | Genotype | Healthy controls (N = 568) | CRC patients (N = 436) | p | OR(95% CI) |
---|---|---|---|---|---|---|---|
-537 | 0.999 | 0.42 | GG | 203 (35.7%) | 127 (29.1%) | 0.025 | 1.373 (1.041–1.810) |
 |  |  | GA or AA | 365 (64.3%) | 309 (70.9%) |  |  |
-277 | 0.548 | 0.07 | TT | 489 (86.1%) | 388 (89.0%) | 0.125 | 0.735 (0.495–1.090) |
 |  |  | TC or CC | 79 (13.9%) | 48 (11.0%) |  |  |
-158 | 0.314 | 0.03 | GG | 522 (91.9%) | 416 (95.4%) | 0.032 | 0.539 (0.307–0.947) |
 |  |  | GA or AA | 46 (8.1%) | 20 (4.6%) |  |  |