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Table 1 Odds Ratios (95% CI) of gastric cancer according to the collected variables and their frequency distribution among 107 cases and 254 controls

From: Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in an Italian population

 

Cases % (n)

Controls % (n)

OR (95% CI) †

Age (years ± SD)

66.4 ± 12.0

64.0 ± 12.8

-

Male gender

52.3 (56)

55.5 (141)

-

Alcohol drinkers

   

   Non-drinkers°

29.9 (32)

47.6 (121)

1*

   Drinkers

70.1 (73)

52.4 (133)

2.10 (1.22–3.60)

Smoking status

   

   Never

53.3 (57)

57.5 (146)

1*

   Ever

46.7 (50)

42.5 (108)

1.10 (0.64–1.90)

Fruit and vegetables intake

   

   High‡

20.0 (21)

15.8 (40)

1*

   Low

80.2 (85)

84.2 (213)

0.95 (0.50–1.90)

Grilled meat

   

   ≤ 2 times/month

52.3 (56)

48.4 (123)

1*

   > 2 times/month

47.7 (61)

51.6 (131)

0.99 (0.60–1.66)

Meals salt addition^

   

   No

85.1 (91)

92.9 (235)

1*

   Yes

14.9 (16)

7.1 (18)

1.70 (0.78–3.67)

Familiarity for cancer

   

   No

61.6 (61)

78.4 (192)

1*

   Yes

38.4 (38)

21.6 (53)

1.93 (1.14–3.26)

Familiarity for gastric cancer

   

   No

88.0 (88)

94.4 (237)

1*

   Yes

12.0 (12)

5.6 (14)

1.88 (0.80–4.44)

  1. * Reference category; † OR adjusted for age, gender, alcohol consumption and familiarity for cancer; ‡ High fruit and vegetables consumption is defined as at least 2 portions of fruit and 2 portions of vegetables per day; ° Non-drinkers defined as an alcohol intake less than 7 g/day; ^ adding salt to the entrées during the main meals