Intratumoral delivery of IL-18 naked DNA induces T-cell activation and Th1 response in a mouse hepatic cancer model

Table 1 Frequency of CD4⁺CD62^Low, CD8⁺CD62^Low, DX5⁺, CD19⁺cells in spleen and blood: major subsets

Spleen and blood samples of CT26 tumor-bearing mice treated with pCEP4 or mIL-18 plasmid DNA were harvested 7 days after gene treatment, and cells analyzed by flow cytometry using the corresponding FITC-, PE-, or PE-Cy5-conjugated antibodies and isotype control. Data are presented as means ± SD of 8 mice/group. ^a P < 0.04, compared with the pCEP4 control-treated group.

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