Table 1 Linear regression analysis to determine which methyl-sensitive restriction enzymes were effective in CpGlobal.
From: A high-throughput and sensitive method to measure Global DNA Methylation: Application in Lung Cancer
Enzyme | Theoretical Regression | Actual Regression | Adjusted R Square | Standard Error | F significance |
|---|---|---|---|---|---|
AciI | y = 1.57-1.57x | y = 0.45-0.46x | 0.86 | 0.06 | 1.11E-09 |
BstUI | y = 0.48-0.48x | y = 0.09-0.11x | 0.87 | 0.01 | 4.39E-10 |
HinP1I | y = 0.66-0.66x | y = 0.95-0.89x | 0.97 | 0.05 | 1.24E-15 |
HpaII | y = 1.00-1.00x | y = 0.94-0.95x | 0.96 | 0.06 | 4.46E-15 |
HpyCH4IV | y = 0.44-0.44x | y = 0.74-0.73x | 0.97 | 0.04 | 7.67E-17 |