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Table 3 Number of genes altered as a function of the treatment type

From: Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines

Treatment type

E

Cx10

Gb

Cx10 + E

Gb + E

 

Down

Up

Down

Up

Down

Up

Down

Up

Down

Up

HT-29

855

544

465

287

1253

885

217

459

799

582

Caco-2

1134

915

541

731

577

868

238

57

226

64

Intersection

274

124

58

49

113

138

3

0

32

10

  1. E = Epidermal growth factor 10 nmol/L; Cx10 = cetuximab 10 nmol/L; Gb = gefitinib 1 μmol/L;
  2. Cx10 + E = cetuximab 10 nmol/L + Epidermal growth factor 10 nmol/L; Gb + E = gefitinib 1 μmol/L + Epidermal growth factor 10 nmol/L; Down = 1/2 fold; Up = 2 fold.