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Figure 1 | BMC Cancer

Figure 1

From: Cell-cycle and suppressor proteins expression in uterine cervix in HIV/HPV co-infection: comparative study by tissue micro-array (TMA)

Figure 1

Expression of Elf-1 in HIV+/HPV+ co-infected cervical tissues. Panel A and B shows Elf-1 expression in ectocervical epithelium negative for CIN and CIN I respectively. Note that the signal is seen mainly in the basal layer of the epithelium (100× and 200×, respectively). Panel C – shows that the signal was evident only in the dysplastic cells in the CIN II lesion (100×). Panel D demonstrates that the Elf-1 signal tends to be more prominent in the squamous component as compared to the negative endocervical tissue (200×). Panel E – The signal in the squamous cell carcinoma tissues also localized to the neoplastic squamous cells (100×). However, neoplastic glandular cells demonstrated a multifocal signal as compared to the negative unremarkable endocervical tissue (panel F, 400×).

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