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Table 1 Patient characteristics

From: Incidence of reversible amenorrhea in women with breast cancer undergoing adjuvant anthracycline-based chemotherapy with or without docetaxel

 

6 FEC 100

3 FEC/3D

Total number of patients (154)

84

70

Median age (range)

43.5 (28–58)

44 29–53)

Patients < 40 years (n = 39)

18 (21.5 %)

21 (30 %)

Patients ≥ 40 years (n = 115)

66 (78 %)

49 (70 %) (p = 0.08)

Hormone receptor status

  

Positive (ER and/or PR)

61 (72.6 %)

53 (75.9 %)

Negative (ER and PR)

23 (27.4 %)

17 (24.1 %)

ER positive

60 (71.4 %)

52 (74.2 %)

ER negative

24 (28.5 %)

18 (25.7 %)

PR positive

50 (59.5 %)

44 (62.8 %)

PR negative

34 (40.4 %)

26 (37.1 %)

Median tumor size (range)

  

Tumor grade

  

I

8 (9.5 %)

6 (8.6 %)

II

34 (40.5 %)

30 (42.8 %)

III

42 (50 %)

34 (48.6 %)

Number of metastatic lymph nodes

  

< 4

66 (78.6 %)

53 (75.9 %)

≥ 4

18 (21.4 %)

17 (24.1 %)

Tumor size

  

T1

25 (29.7 %)

21 (30 %)

T2

50 (59.5 %)

42 (60 %)

T3

9 (10.8 %)

7 (10 %)

  1. ER: estrogen receptor; PR: progesterone receptor
  2. (p-value never < 0.05)