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Table 3 Overview of prognostic factors in the present group of patients

From: Prognostic scores in brain metastases from breast cancer

Parameter

Univariate analysis (log rank test)

Multivariate analysis (Cox regression analysis)

Included in final prognostic model

Primary tumor control

not done

  

Age

not significant (p = 0.09)

not significant (p > 0.01)

 

Karnofsky performance status

p < 0.05

p = 0.01, hazard ratio 3.6

yes

Extracranial metastases

p < 0.05

p = 0.03, hazard ratio 2.1

yes

Interval from first cancer diagnosis to brain metastases

p < 0.05

p = 0.05, hazard ratio 1.8

yes

Number of brain metastases

p < 0.05

p = 0.05, hazard ratio 2.0

yes

Diameter of the largest brain metastasis

not significant (p > 0.1)

not included

 

Hormone receptor status

not significant (p > 0.1)

not included

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