Figure 3From: Activation of P2X7-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice Summary of the effects of local treatments with DMBA/TPA (black symbols) or DMBA/TPA+BzATP (white symbols) on the proportion of living mice with skin lesions (Experiment-1). In A, skin lesions at 0–12 weeks of treatment were papillomas. In A and B, skin lesions at 14–28 weeks of treatment were grouped either as cancerous lesions (squamous spindle-cell carcinomas, circles), or as non-cancerous lesions (existing or involuting papillomas, triangles). Values in A and B are means; standard deviation (SD) ranged 3–11%.Back to article page