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Table 5 Concordance of IHC and FISH results by Kappa statistics

From: Inter-observer reproducibility of HER2 immunohistochemical assessment and concordance with fluorescent in situhybridization (FISH): pathologist assessment compared to quantitative image analysis

 

FISH vs categorized

IHC (n = 616)

FISH vs binarized

IHC (n = 382)

Visual 1

0.814 (0.768 – 0.856)

0.328 (0.0955 – 0.537)

Visual 2

0.763 (0.712 – 0.81)

0.328 (0.0914 – 0.538)

Machine 1

0.665 (0.609 – 0.718)

0.343 (0.101 – 0.558)

Machine 2

0.535 (0.485 – 0.584)

0.343 (0.0935 – 0.555)

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BMC Cancer

ISSN: 1471-2407

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