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Table 3 Proportional Hazards Model of Malignant Transformation for Related Factors(n = 148)1

From: Malignant transformation of oral potentially malignant disorders in males: a retrospective cohort study

Variable

 

RR

95%CI

P value

ARR

95%CI

P value

Age

<=45 years

1.00

  

1.00

  
 

> 45 years

1.42

(0.93,2.22)

0.1007

1.42

(0.90,2.31)

0.1184

OPMDs

Hyperkeratosis or epithelial hyperplasia

1.00

  

1.00

  
 

Verrucous hyperplasia

1.38

(0.81,2.44)

0.2304

1.23

(0.66,2.31)

0.5077

 

Epithelial dysplasia

1.56

(0.92,2.82)

0.0991

1.51

(0.86,2.73)

0.1493

Location

Buccal2

1.00

  

1.00

  
 

Tongue

2.31

(1.46,3.71)

< 0.001

2.41

(1.43,4.16)

0.0012

 

Other3

1.34

(0.62,2.50)

0.4103

1.37

(0.62,2.68)

0.4062

Smoking

No

1.00

  

1.00

  
 

Yes

0.77

(0.47,1.44)

0.3958

0.98

(0.48,2.31)

0.9556

Alcohol use

No

1.00

  

1.00

  
 

Yes

0.99

(0.65,1.58)

0.9809

1.10

(0.68,1.87)

0.7134

Areca quid use

No

1.00

  

1.00

  
 

Yes

0.53

(0.28,1.34)

0.1505

0.98

(0.36,2.97)

0.9682

  1. 1: OSF cases are excluded in this table
  2. 2: Including buccal, vestibule and retromolar
  3. 3: Including lip, gingival, palate