Figure 6
From: Vasohibin inhibits angiogenic sprouting in vitro and supports vascular maturation processes in vivo
Effects of stable overexpression of mVASH1 on tumor microvessel growth and maturation. (A) Representative image of CD31 stained blood vessels in controls and VASH1 overexpressing melanomas. Bars indicate 50 μm. (B) Cryosections of all tumors were analyzed by co-staining for the endothelial marker CD31 together with the pericyte marker NG2 or the smooth muscle cell marker ASMA. Bars indicate 20 μm (C) Statistical analysis of microvessels in controls and mVASH1-overexpressing tumors. HPF indicates high power field (200×).