Preoperative serum carcinoembryonic antigen, albumin and age are supplementary to UICC staging systems in predicting survival for colorectal cancer patients undergoing surgical treatment

Table 9 Univariate and multivariate analysis of prognostic indicators on overall survival for stage III colorectal cancer patients

Parameters	Number	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI) P value		Hazard ratio (95% CI) P value
Age (≥65/<65) years	189/193	1.87(1.33–2.65)	<0.001	1.87(1.33–2.65)	<0.001
Sex (Male/Female)	198/184	1.38(0.96–2.00)	0.086	-	-
Site (Colon/Rectum)	263/119	1.01(0.70–1.46)	0.961	-	-
Tumor size (≥5/<5) cm	170/212	1.17(0.82–1.65)	0.393	-	-
BMI^a (≥24/<18.5–24/<18.5)	123/150/109	0.99(0.63–1.59)	0.987	-	-
Albumin (<3.5/≥3.5) gm/dl	110/272	1.38(0.89–2.14)	0.156	-	-
Histology (PD/MD/WD^b)	62/278/42	2.15(0.97–4.74)	0.058	-	-
CEA^c(≥5/<5) ng/ml	193/189	1.43(1.02–2.02)	0.039	1.43(1.02–2.02)	0.039

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