From: Cripto-1 overexpression is involved in the tumorigenesis of nasopharyngeal carcinoma
 |  | Cripto-1 |  | |
---|---|---|---|---|
Clinicopathological variables | Cases (n = 37) | positive (%) | negative (%) | pvalue |
 |  | n = 20 | n = 17 |  |
Gender | Â | Â | Â | 0.627 |
   Male | 26 | 14 (53.8) | 12 (46.2) |  |
   Female | 11 | 6 (54.5) | 5 (45.5) |  |
Age(years) a | Â | Â | Â | 0.540 |
   ≤ 49 | 21 | 11(52.4) | 10 (47. 6) |  |
   >49 | 16 | 9 (56.3) | 7 (43.7) |  |
Pathological classification(WHO) | Â | Â | Â | 0.062 |
Type I-II | 17 | 12(70.6) | 5 (29.4) | Â |
Type III | 20 | 8 (40.0) | 12 (60.0) | Â |
Depth of invasion T classification | Â | Â | Â | 0.474 |
   T1-2 | 27 | 14(51.9) | 13 (48.1) |  |
   T3-4 | 10 | 6(60) | 4(40) |  |
Lymph node metastasis N classification | Â | Â | Â | 0.034c |
N0 | 9 | 2 (22.2) | 7 (77.8) | Â |
N1-3 | 28 | 18(64.3) | 10 (35.7) | Â |
Distant metastasis | Â | Â | Â | 0.036c |
   Yes | 5 | 5(100.0) | 0(0.0) |  |
   No | 32 | 15 (48.4) | 17(51.6) |  |
Clinical Staging b | Â | Â | Â | 0.007c |
I-II | 15 | 4 (26.7) | 11 (73.3) | Â |
III-IV | 22 | 16(72.7) | 6(27.3) | Â |