Figure 4
From: STK33 overexpression in hypopharyngeal squamous cell carcinoma: possible role in tumorigenesis
Effects of STK33-RNAi and/or PD98059 on mRNA and protein expressions of genes relevant to apoptosis and proliferation of Fadu cells. Real-time PCR (A) and western blot (B, C) showed STK33-RNAi significantly increased the expression of Caspase-3 in Fadu cells at 96 h post-transfection. Meanwhile, STK33-RNAi markedly decreased the expressions of Bcl-2 and Ki-67 in Fadu cells, and the effects were potentiated by PD98059. Results were shown as the means ± SEM, n = 3. *P < 0.05.