Table 4 Multivariate logistic regression analysis showing associations of relevant histopathological features in non-metastatic (N0/M0) versus lymphogenous-metastatic (N+) and haematogenous-metastatic (M+) CC
From: Histopathological features predict metastatic potential in locally advanced colon carcinomas
| Â | N0/M0 vs. N+ | N0/M0 vs. M+ | ||
|---|---|---|---|---|
| Â | OR (95% CI) | p-value | OR (95% CI) | p-value |
Tumor budding low vs. high | 5.99 (1.28-27.90) | 0.023 | 8.70 (1.83-41.42) | 0.007 |
Inflammation zone 1 lymphocytic vs.non-lymphocytic | 0.06 (0.01-0.52) | 0.012 | 0.20 (0.03-1.38) | NS |
Tumor/Necrosis ratio (> median, ≤median) |  |  | 0.46 (0.13-1.62) | NS |
Tumor/Desmoplasia ratio (> median, ≤median) | 0.17 (0.04-0.73) | 0.017 |  |  |
Desmoplastic pattern finger-like vs. non-finger-like | 0.18 (0.03-0.89) | 0.037 | Â | Â |
Large vessel density zone 3 (> median, ≤median) | 2.437 (0.61-9.69) | NS |  |  |
Small vessel density zone 1 (> median, ≤median) |  |  | 0.33 (0.09-1.23) | NS |