Table 2 Correlation of EphA5 methylation and mRNA expression with clinical and histological parameters in PCa patients
From: Downregulation of EphA5 by promoter methylation in human prostate cancer
Methylation | p-value1 | mRNA expression | p-value1 | |||
|---|---|---|---|---|---|---|
Present | Absent | Normal | Reduced | |||
Age (years) | ||||||
≤70 | 18 | 7 | 0.883 | 8 | 17 | 0.371 |
>70 | 14 | 6 | 9 | 11 | ||
PSA (ng/ml) | ||||||
≤10 | 6 | 3 | 0.742 | 2 | 7 | 0.537 |
>10 | 26 | 10 | 15 | 21 | ||
Stage (TNM) | ||||||
T1-T2 | 6 | 7 | 0.019 | 7 | 6 | 0.156 |
T3-T4 | 26 | 6 | 10 | 22 | ||
Gleason score | ||||||
6-7 | 12 | 10 | 0.016 | 12 | 10 | 0.023 |
8-10 | 20 | 3 | 5 | 18 | ||
Prostate volume (ml) | ||||||
≤50 | 24 | 7 | 0.165 | 11 | 20 | 0.637 |
>50 | 8 | 6 | 6 | 8 | ||