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Table 6 Percentage distribution of the VEGFR-1 ligands, VEGFR-1 and pVEGFR-1 in inflammatory cells of CC tissue

From: Cell type- and tumor zone-specific expression of pVEGFR-1 and its ligands influence colon cancer metastasis

 

N0/M0 (%)

N+ (%)

M+ (%)

z1

z2

z1

N0/M0 vs. N + p

z2

N0/M0 vs. N + p

z1

N0/M0 vs. M + p

z2

N0/M0 vs. M + p

VEGF

3

5

5

NS 1.0

18

NS 0.2

5

NS 1.0

8

NS 1.0

PlGF

69

84

78

NS 0.7

95

NS 0.2

71

NS 1.0

79

NS 0.7

VEGF-B

0

0

0

 

0

 

0

 

0

 

VEGFR-1

67

92

50

NS 0.2

82

NS 0.4

59

NS 0.6

68

0.02

pVEGFR-1 Tyr1048

83

95

68

NS 0.3

91

NS 0.6

68

NS 0.2

80

NS 0.1

pVEGFR-1 Tyr1213

60

64

33

NS 0.1

50

NS 1.0

50

NS 0.6

56

NS 0.8

pVEGFR-1 Tyr1333

75

86

67

NS 0.5

68

NS 0.1

72

NS 1.0

68

NS 0.1

  1. z1 = zone 1, z2 = zone 2. p < 0.05 statistically significant. NS, not significant.