Figure 1From: Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an independent prognostic marker in wild-type KRAS metastatic colorectal cancer after colorectal liver metastasectomyModel of CIP2A involvement in the EGFR-RAS signaling pathways. ETS1 mediates CIP2A overexpression in human cancers with increased EGFR-MEK-ERK pathway activity. A positive feedback loop of CIP2A and MEK/ERK signaling pathways is shown.Back to article page