Table 1 Association between clinicopathological parameters and CIP2A expression in patients after colorectal liver metastasectomy

Sex

Female

44

(53.7)

38

(46.3)

0.248

Male

85

(61.6)

53

(38.4)

Age (y/o)

≤65

80

(63.5)

46

(36.5)

0.090

>65

49

(52.1)

45

(47.9)

Initial stage at diagnosis

I-III

57

(44.2)

30

(33.0)

0.094

IV

72

(55.8)

61

(67.0)

Location

Colon

88

(57.5)

65

(42.5)

0.610

Rectum

41

(61.2)

26

(38.8)

Pathology

Adenocarcinoma

127

(59.6)

86

(40.4)

0.101

Mucinous adenocarcinoma

2

(28.6)

5

(71.4)

Grade

Low

121

(93.8)

90

(98.9)

0.060

High

8

(6.2)

1

(1.1)

Margin

R0-1

125

(96.9)

88

(96.7)

0.935

R2

4

(3.1)

3

(3.3)

Distribution

Unilateral

113

(59.8)

76

(40.2)

0.392

Bilateral

16

(51.6)

15

(48.4)

Number

≤3

101

(60.1)

67

(39.9)

0.422

>3

28

(53.8)

24

(46.2)

Size (cm)

≤5

107

(59.8)

72

(40.2)

0.473

>5

22

(53.7)

19

(46.3)

Extrahepatic metastasis

No

107

(82.9)

74

(81.3)

0.756

Yes

22

(17.1)

17

(18.7)

KRAS

Wild-type

91

(69.5)

40

(30.5)

<0.001

Codon 12 mutation

28

(42.4)

38

(57.6)

G12D

13

(40.6)

19

(59.4)

G21V

7

(41.2)

10

(58.8)

G12C

5

(41.7)

7

(58.3)

G12R

1

(100.0)

0

(0.0)

G12S

2

(50.0)

2

(50.0)

Codon 13 mutation

10

(45.5)

12

(54.5)

G13D

9

(45.0)

11

(55.0)

G13C

0

(0.0)

1

(100.0)

G13V

1

(100.0)

0

(0.0)

Codon 14 mutation

0

(0.0)

1

(100.0)

V14I

0

(0.0)

1

(100.0)